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Naval Medical Research
and Development
Enterprise Laboratories
  • Naval 
Medical Research Unit - DaytonNaval Medical Research Center Unit - Dayton
    Dayton, OH
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 Directorates

Administration Directorate

     The mission of the Command Administration Directorate is to be the pinnacle of administrative support to Naval Medical Research Unit Dayton leadership, science directorates, military personnel and civilian staff. The directorate guides the command on administrative matters pertaining to health and medical research, development, testing, evaluation, and surveillance. The Administration Directorate manages several logistic and auxiliary programs, including personnel human resourcing, information systems, supply chain management, and administrative requirements in support of vital command mission functions. The directorate also provides oversight and management of several integral command roles, including safety and hazardous material programs, directives, instructions and policy generation, security and classified material oversight, ICONO audit readiness, manpower and billet analysis / requirements, intellectual property, agreements, contracting / contracting officer representative actions, and support service functions. These efforts are key pillars of support that sustain a seamless civilian support program while simultaneously ensuring our military personnel meet all deployment and readiness requirements.

Aeromedical Research

     NAMRU-D research capabilities in the visual, vestibular, and cognitive sciences are supported by a unique collection of state-of-the-science equipment and research devices. NAMRU-D’s human-rated motion platforms include the Disorientation Research Device (DRD), the Visual Vestibular Sphere Device (VVSD), the Vertical Linear Accelerator (VLA), and the Neuro-Otologic Test Center (NOTC). Each device is capable of unique motion profiles, affording independent control of visual and vestibular stimuli to isolate sensory interactions associated with spatial disorientation and motion sickness. NAMRU-D’s hypoxia program is supported by a lab suite capable of running up to six Reduced Oxygen Breathing Devices, each of which can simulate altitude exposures at up to 34k' under normobaric conditions. NAMRU-D facilities also house a vision suite containing a full array of ophthalmic equipment. This unique assortment of capabilities enables NAMRU-D to transition validated knowledge and effective technologies to the fleet that will mitigate and prevent leading factors associated with aeromedical mishaps.NAMRU-D research capabilities in the visual, vestibular, and cognitive sciences are supported by a unique collection of state-of-the-science equipment and research devices. NAMRU-D’s human-rated motion platforms include the Disorientation Research Device (DRD), the Visual Vestibular Sphere Device (VVSD), the Vertical Linear Accelerator (VLA), and the Neuro-Otologic Test Center (NOTC). Each device is capable of unique motion profiles, affording independent control of visual and vestibular stimuli to isolate sensory interactions associated with spatial disorientation and motion sickness. NAMRU-D’s hypoxia program is supported by a lab suite capable of running up to six Reduced Oxygen Breathing Devices, each of which can simulate altitude exposures at up to 34k' under normobaric conditions. NAMRU-D facilities also house a vision suite containing a full array of ophthalmic equipment. This unique assortment of capabilities enables NAMRU-D to transition validated knowledge and effective technologies to the fleet that will mitigate and prevent leading factors associated with aeromedical mishaps.

Environmental Health Effects Research

The Environmental Health Effects Research Directorate assesses the environmental and occupational health risks to our soldiers, sailors, airmen and marines with unique and state-of-the-art technologies. The inhalation systems are equipped with a diverse suite of analytical instrumentation capable of monitoring precise exposures to gases, vapors, aerosols, and particulates, including nanoparticles, as well as environmental conditions such as humidity, pressure, and temperature that may effect a response. Whole-body inhalation chambers and nose-only inhalation systems are fully automated to minimize manpower requirements for regulating test atmospheres and ensuring accurate data collection. Leach-style chambers are used for vapor uptake studies in rodents to provide data for physiologically based pharmacokinetic (PBPK) models. Research in neurobehavioral/cognitive sciences are supported by a proprietary neurobehavioral test battery, which assess exposure-induced changes in animals for motor coordination, locomotor function, emotionality, as well as learning and memory. Our facility also houses six primary labs dedicated to advanced bioinformatics, including genomics, transcriptomics, molecular biology, biochemical and analytical chemistry, with a tissue culture facility and state-of-the-art equipment in flow-cytometry and RT-PCR to identify mechanisms of toxic action and identify biomarkers of environmental toxicants that may affect the warfighter’s health.The Environmental Health Effects Research Directorate assesses the environmental and occupational health risks to our soldiers, sailors, airmen and marines with unique and state-of-the-art technologies. The inhalation systems are equipped with a diverse suite of analytical instrumentation capable of monitoring precise exposures to gases, vapors, aerosols, and particulates, including nanoparticles, as well as environmental conditions such as humidity, pressure, and temperature that may effect a response. Whole-body inhalation chambers and nose-only inhalation systems are fully automated to minimize manpower requirements for regulating test atmospheres and ensuring accurate data collection. Leach-style chambers are used for vapor uptake studies in rodents to provide data for physiologically based pharmacokinetic (PBPK) models. Research in neurobehavioral/cognitive sciences are supported by a proprietary neurobehavioral test battery, which assess exposure-induced changes in animals for motor coordination, locomotor function, emotionality, as well as learning and memory. Our facility also houses six primary labs dedicated to advanced bioinformatics, including genomics, transcriptomics, molecular biology, biochemical and analytical chemistry, with a tissue culture facility and state-of-the-art equipment in flow-cytometry and RT-PCR to identify mechanisms of toxic action and identify biomarkers of environmental toxicants that may affect the warfighter’s health.
 
These capabilities have increased Tri-Service collaboration and enhanced the research activities associated with force health protection. NAMRU-D inhalation scientists are currently collaborating with Air Force Toxicologists in several research areas, including jet fuel toxicity and jet fuel plus noise co-exposures studies.
Directorates